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Endothelial Growth Factors MeSH Descriptor Data 2021


MeSH Heading
Endothelial Growth Factors
Tree Number(s)
D12.644.276.390
D12.776.467.390
D23.529.390
Unique ID
D016228
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016228
Annotation
do not confuse with EGF; (EPIDERMAL GROWTH FACTOR)
Scope Note
These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
Entry Version
ECGF
Entry Term(s)
ECDGF
Endo-GF
Endothelial Cell-Derived Growth Factors
Endothelial Growth Factor
Endothelial Growth Factor Polypeptides
alpha-Endothelial Growth Factor
beta-Endothelial Growth Factor
Pharm Action
Growth Substances
Registry Number
0
Previous Indexing
Fibroblast Growth Factor (1984-1990)
Growth Substances (1966-1983)
See Also
Vascular Endothelial Growth Factor A
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/05/30
Revision Date
2006/07/05
Endothelial Growth Factors Preferred
beta-Endothelial Growth Factor Narrower
alpha-Endothelial Growth Factor Narrower
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