MeSH Browser

MeSH Heading: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Tree Number(s): D08.811.682.660.465
Unique ID: D013741
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013741
Scope Note: An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.
Entry Term(s): 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase; 3-oxo-5 alpha-Steroid 4-Dehydrogenase (NADP+); 3-oxo-5alpha-Steroid 4-Dehydrogenase (NADP+); 4-Ene-3-Oxosteroid-5alpha-Reductase; 4-Ene-5-alpha-Reductase; 5-alpha-Reductase, Testosterone; NADH-5-alpha-Reductase; NADPH delta(4)-3-Ketosteroid 5 alpha-Oxidoreductase; Steroid 5-alpha-Reductase; Steroid 5Alpha Reductase; Steroid delta-4-5-alpha Reductase; Testosterone 5-alpha-Reductase; Testosterone delta-4-5-alpha-Reductase; delta 4-3-keto Steroid 5 alpha-Oxidoreductase; delta(4)-3-Ketosteroid-5alpha-Reductase; delta4-3-ketosteroid 5alpha-Oxidoreductase
CAS Type 1 Name: 3-Oxo-5 alpha-steroid:(acceptor) delta(4)-oxidoreductase
Previous Indexing: Oxidoreductases (1972-1974); Testosterone (1972-1974)
Public MeSH Note: 2010; see TESTOSTERONE 5-ALPHA REDUCTASE 1986-2010, see OXIDOREDUCTASES 1975-1985
History Note: 2010(1975)
Entry Combination: antagonists & inhibitors:5-alpha Reductase Inhibitors
Date Established: 1986/01/01
Date of Entry: 1974/11/19
Revision Date: 2014/11/21

Entry Combination: antagonists & inhibitors:5-alpha Reductase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

3-Oxo-5-alpha-Steroid 4-Dehydrogenase MeSH Descriptor Data 2025