NLM Logo

Isovaleryl-CoA Dehydrogenase MeSH Descriptor Data 2023


MeSH Heading
Isovaleryl-CoA Dehydrogenase
Tree Number(s)
D08.811.682.660.462
Unique ID
D050769
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050769
Scope Note
A mitochondrial flavoprotein, this enzyme catalyzes the oxidation of 3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA using FAD as a cofactor. Defects in the enzyme, is associated with isovaleric acidemia (IVA).
Entry Term(s)
Isovaleryl CoA Dehydrogenase
Isovaleryl-Coenzyme A Dehydrogenase
Registry Number
EC 1.3.8.4
Related Numbers
37274-61-6
Previous Indexing
Acyl Coenzyme A (1980-1982)
Coenzyme A (1973-1980)
Oxidoreductases (1983-2003)
Oxidoreductases Acting on CH-CH Group Donors (2004-2005)
Valerates (1973-1982)
Public MeSH Note
2006; ISOVALERYL-COA DEHYDROGENASE was indexed under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005, under OXIDOREDUCTASES 1983-2003, under ACYL COENZYME A 1980-1982, COENZYME A 1973-1980, and under VALERATES 1973-1982
History Note
2006(1973)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/06/28
Isovaleryl-CoA Dehydrogenase Preferred
page delivered in 0.164s