MeSH Browser

MeSH Heading: Glutaryl-CoA Dehydrogenase
Tree Number(s): D08.811.682.660.425
Unique ID: D050770
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050770
Scope Note: A flavoprotein enzyme that is responsible for the catabolism of LYSINE; HYDROXYLYSINE; and TRYPTOPHAN. It catalyzes the oxidation of GLUTARYL-CoA to crotonoyl-CoA using FAD as a cofactor. Glutaric aciduria type I is an inborn error of metabolism due to the deficiency of glutaryl-CoA dehydrogenase.
Entry Term(s): Glutaryl CoA Dehydrogenase; Glutaryl-Coenzyme A Dehydrogenase
Registry Numbers: EC 1.3.8.6
Related Numbers: 37255-38-2
Previous Indexing: Acyl Coenzyme A (1973-1979); Coenzymes (1973-1979); Glutarates (1973-1980); Oxidoreductases (1983-2003); Oxidoreductases Acting on CH-CH Group Donors (2004-2005)
Public MeSH Note: 2006; GLUTARYL-COA DEHYDROGENASE was indexed under ACYL COENZYME A 1973-1979; under GLUTARATES 1973-1982; and under COENZYME A 1973-1979; under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005
History Note: 2006(1973)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0074614
Registry Numbers: EC 1.3.8.6
Related Numbers: 37255-38-2
Scope Note: A flavoprotein enzyme that is responsible for the catabolism of LYSINE; HYDROXYLYSINE; and TRYPTOPHAN. It catalyzes the oxidation of GLUTARYL-CoA to crotonoyl-CoA using FAD as a cofactor. Glutaric aciduria type I is an inborn error of metabolism due to the deficiency of glutaryl-CoA dehydrogenase.
Terms: Glutaryl-CoA Dehydrogenase Preferred Term
Term UI T104617
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glutaryl CoA Dehydrogenase
Term UI T104615
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glutaryl-Coenzyme A Dehydrogenase
Term UI T104616
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Glutaryl-CoA Dehydrogenase MeSH Descriptor Data 2025