MeSH Browser

MeSH Heading: Cholestenone 5 alpha-Reductase
Tree Number(s): D08.811.682.660.200
Unique ID: D042944
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D042944
Scope Note: An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.
Entry Term(s): 4-Ene Steroid 5 alpha-Reductase; 5 alpha-Reductase
Related Numbers: 37255-34-8; EC 1.3.1.22
Previous Indexing: Cholestenones (1970-1982); Oxidoreductases (1983-2003)
Public MeSH Note: 2004; CHOLESTENONE 5 ALPHA-REDUCTASE was indexed under OXIDOREDUCTASES 1983-2003 & under CHOLESTENONES 1970-1982
History Note: 2004; use CHOLESTENONE 5 ALPHA-REDUCTASE (NM) 1980-2003
Entry Combination: analogs & derivatives:5-alpha Reductase Inhibitors
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2015/11/10

Entry Combination: analogs & derivatives:5-alpha Reductase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0072874
Related Numbers: 37255-34-8; EC 1.3.1.22
Scope Note: An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.
Terms: Cholestenone 5 alpha-Reductase Preferred Term
Term UI T102877
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); 4-Ene Steroid 5 alpha-Reductase
Term UI T102875
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); 5 alpha-Reductase
Term UI T102876
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Cholestenone 5 alpha-Reductase MeSH Descriptor Data 2025