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Cholestenone 5 alpha-Reductase MeSH Descriptor Data 2025


MeSH Heading
Cholestenone 5 alpha-Reductase
Tree Number(s)
D08.811.682.660.200
Unique ID
D042944
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D042944
Scope Note
An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.
Entry Term(s)
4-Ene Steroid 5 alpha-Reductase
5 alpha-Reductase
Related Numbers
37255-34-8
EC 1.3.1.22
Previous Indexing
Cholestenones (1970-1982)
Oxidoreductases (1983-2003)
Public MeSH Note
2004; CHOLESTENONE 5 ALPHA-REDUCTASE was indexed under OXIDOREDUCTASES 1983-2003 & under CHOLESTENONES 1970-1982
History Note
2004; use CHOLESTENONE 5 ALPHA-REDUCTASE (NM) 1980-2003
Entry Combination
analogs & derivatives:5-alpha Reductase Inhibitors
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2015/11/10
Cholestenone 5 alpha-Reductase Preferred
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