MeSH Browser

MeSH Heading: Dihydrouracil Dehydrogenase (NADP)
Tree Number(s): D08.811.682.660.350
Unique ID: D042943
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D042943
Scope Note: An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.
Entry Term(s): Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase (NADP)
Previous Indexing: Oxidoreductases (1980-2003); Uracil (1979)
Public MeSH Note: 2004; DIHYDROURACIL DEHYDROGENASE (NADP) was indexed under OXIDOREDUCTASES 1983-2003; & under URACIL 1979
History Note: 2004; use DIHYDROURACIL DEHYDROGENASE (NADP) (NM) 1980-2003
Entry Combination: deficiency:Dihydropyrimidine Dehydrogenase Deficiency
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2013/07/08

Entry Combination: deficiency:Dihydropyrimidine Dehydrogenase Deficiency
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Dihydrouracil Dehydrogenase (NADP) MeSH Descriptor Data 2025