MeSH Browser

MeSH Heading: Organic Anion Transport Protein 1
Tree Number(s): D12.776.157.530.450.074.500.781.750; D12.776.157.530.937.610; D12.776.543.585.450.074.500.875.750; D12.776.543.585.450.162.234; D12.776.543.585.937.719
Unique ID: D027362
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D027362
Scope Note: A polyspecific transporter for organic cations found primarily in the kidney. It mediates the coupled exchange of alpha-ketoglutarate with organic ions such as P-AMINOHIPPURIC ACID.
Entry Term(s): OAT1 Protein; PAH Transporter; Renal PAN transporter; SLC22A6 Transporter; Solute Carrier Family 22 (Organic Anion Transporter), Member 6; p-Aminohippurate Transporter
Previous Indexing: Carrier Proteins (1997-2001); Membrane Proteins (1997-2001)
Public MeSH Note: 2002; OAT1 PROTEIN, P-AMINOHIPPURATE TRANSPORTER & RENAL PAN TRANSPORTER were indexed under CARRIER PROTEINS 2000-2001
History Note: 2002; for OAT1 PROTEIN, P-AMINOHIPPURATE TRANSPORTER & RENAL PAN TRANSPORTER use ANION TRANSPORT PROTEINS 2000-2001
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Pumps [D12.776.157.530.450]
        
        Anion Transport Proteins [D12.776.157.530.450.074]
        
        Organic Anion Transporters [D12.776.157.530.450.074.500]
        
        Organic Anion Transporters, Sodium-Independent [D12.776.157.530.450.074.500.781]
        
        Liver-Specific Organic Anion Transporter 1 [D12.776.157.530.450.074.500.781.500]
        
        Organic Anion Transport Protein 1 [D12.776.157.530.450.074.500.781.750]
        
        Solute Carrier Organic Anion Transporter Family Member 1B3 [D12.776.157.530.450.074.500.781.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Solute Carrier Proteins [D12.776.157.530.937]
        
        Amino Acid Transport System X-AG [D12.776.157.530.937.250]
        
        Amino Acid Transport System y+L [D12.776.157.530.937.313]
        
        Amino Acid Transport System y+ [D12.776.157.530.937.375]
        
        Dopamine Plasma Membrane Transport Proteins [D12.776.157.530.937.500]
        
        Equilibrative Nucleoside Transport Proteins [D12.776.157.530.937.532]
        
        Glucose Transport Proteins, Facilitative [D12.776.157.530.937.563]
        
        K Cl- Cotransporters [D12.776.157.530.937.572]
        
        Liver-Specific Organic Anion Transporter 1 [D12.776.157.530.937.580]
        
        Mitochondrial ADP, ATP Translocases [D12.776.157.530.937.594]
        
        Mitochondrial Uncoupling Proteins [D12.776.157.530.937.598]
        
        Norepinephrine Plasma Membrane Transport Proteins [D12.776.157.530.937.600]
        
        Organic Anion Transport Protein 1 [D12.776.157.530.937.610]
        
        Organic Cation Transport Proteins [D12.776.157.530.937.612]
        
        Peptide Transporter 1 [D12.776.157.530.937.613]
        
        Proton-Coupled Folate Transporter [D12.776.157.530.937.618]
        
        Reduced Folate Carrier Protein [D12.776.157.530.937.622]
        
        Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.937.624]
        
        SLC31 Proteins [D12.776.157.530.937.640]
        
        SLC4A Proteins [D12.776.157.530.937.656]
        
        Sodium-Coupled Vitamin C Transporters [D12.776.157.530.937.688]
        
        Sodium-Glucose Transporter 1 [D12.776.157.530.937.696]
        
        Sodium-Glucose Transporter 2 [D12.776.157.530.937.700]
        
        Sodium-Hydrogen Exchangers [D12.776.157.530.937.703]
        
        Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.530.937.704]
        
        Sodium-Phosphate Cotransporter Proteins, Type III [D12.776.157.530.937.719]
        
        Sodium-Potassium-Chloride Symporters [D12.776.157.530.937.750]
        
        Solute Carrier Family 44, Member 2 Protein [D12.776.157.530.937.828]
        
        Solute Carrier Organic Anion Transporter Family Member 1B3 [D12.776.157.530.937.905]
        
        Sulfate Transporters [D12.776.157.530.937.929]
        
        Urea Transporters [D12.776.157.530.937.941]
        
        Zinc Transporter 8 [D12.776.157.530.937.952]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Pumps [D12.776.543.585.450]
        
        Anion Transport Proteins [D12.776.543.585.450.074]
        
        Organic Anion Transporters [D12.776.543.585.450.074.500]
        
        Organic Anion Transporters, Sodium-Independent [D12.776.543.585.450.074.500.875]
        
        Liver-Specific Organic Anion Transporter 1 [D12.776.543.585.450.074.500.875.500]
        
        Organic Anion Transport Protein 1 [D12.776.543.585.450.074.500.875.750]
        
        Solute Carrier Organic Anion Transporter Family Member 1B3 [D12.776.543.585.450.074.500.875.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Pumps [D12.776.543.585.450]
        
        Antiporters [D12.776.543.585.450.162]
        
        Chloride-Bicarbonate Antiporters [D12.776.543.585.450.162.193]
        
        Mitochondrial ADP, ATP Translocases [D12.776.543.585.450.162.225]
        
        Organic Anion Transport Protein 1 [D12.776.543.585.450.162.234]
        
        Potassium-Hydrogen Antiporters [D12.776.543.585.450.162.276]
        
        Reduced Folate Carrier Protein [D12.776.543.585.450.162.359]
        
        Sodium-Calcium Exchanger [D12.776.543.585.450.162.442]
        
        Sodium-Hydrogen Exchangers [D12.776.543.585.450.162.775]
        
        Sodium-Potassium-Exchanging ATPase [D12.776.543.585.450.162.800]
        
        Vesicular Neurotransmitter Transport Proteins [D12.776.543.585.450.162.887]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Solute Carrier Proteins [D12.776.543.585.937]
        
        Amino Acid Transport System X-AG [D12.776.543.585.937.250]
        
        Amino Acid Transport System y+L [D12.776.543.585.937.313]
        
        Amino Acid Transport System y+ [D12.776.543.585.937.375]
        
        Dopamine Plasma Membrane Transport Proteins [D12.776.543.585.937.500]
        
        Equilibrative Nucleoside Transport Proteins [D12.776.543.585.937.563]
        
        Glucose Transport Proteins, Facilitative [D12.776.543.585.937.625]
        
        K Cl- Cotransporters [D12.776.543.585.937.657]
        
        Mitochondrial ADP, ATP Translocases [D12.776.543.585.937.688]
        
        Mitochondrial Uncoupling Proteins [D12.776.543.585.937.696]
        
        Norepinephrine Plasma Membrane Transport Proteins [D12.776.543.585.937.700]
        
        Organic Cation Transport Proteins [D12.776.543.585.937.701]
        
        Peptide Transporter 1 [D12.776.543.585.937.702]
        
        Organic Anion Transport Protein 1 [D12.776.543.585.937.719]
        
        Proton-Coupled Folate Transporter [D12.776.543.585.937.735]
        
        Reduced Folate Carrier Protein [D12.776.543.585.937.743]
        
        Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.937.747]
        
        SLC31 Proteins [D12.776.543.585.937.762]
        
        SLC4A Proteins [D12.776.543.585.937.776]
        
        Sodium-Coupled Vitamin C Transporters [D12.776.543.585.937.813]
        
        Sodium-Glucose Transporter 1 [D12.776.543.585.937.821]
        
        Sodium-Glucose Transporter 2 [D12.776.543.585.937.825]
        
        Sodium-Hydrogen Exchangers [D12.776.543.585.937.828]
        
        Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.543.585.937.829]
        
        Sodium-Phosphate Cotransporter Proteins, Type III [D12.776.543.585.937.844]
        
        Sodium-Potassium-Chloride Symporters [D12.776.543.585.937.875]
        
        Liver-Specific Organic Anion Transporter 1 [D12.776.543.585.937.901]
        
        Solute Carrier Family 44, Member 2 Protein [D12.776.543.585.937.926]
        
        Solute Carrier Organic Anion Transporter Family Member 1B3 [D12.776.543.585.937.950]
        
        Sulfate Transporters [D12.776.543.585.937.963]
        
        Urea Transporters [D12.776.543.585.937.969]
        
        Zinc Transporter 8 [D12.776.543.585.937.975]

Organic Anion Transport Protein 1 Preferred

Concept UI: M0363716
Scope Note: A polyspecific transporter for organic cations found primarily in the kidney. It mediates the coupled exchange of alpha-ketoglutarate with organic ions such as P-AMINOHIPPURIC ACID.
Terms: Organic Anion Transport Protein 1 Preferred Term
Term UI T437927
Date03/05/2001
LexicalTag NON
ThesaurusID NLM (2002); Renal PAN transporter
Term UI T416175
Date06/07/2000
LexicalTag ACX
ThesaurusID NLM (2002); p-Aminohippurate Transporter
Term UI T416176
Date06/07/2000
LexicalTag NON
ThesaurusID NLM (2002); OAT1 Protein
Term UI T416174
Date06/07/2000
LexicalTag ACX
ThesaurusID NLM (2002); Solute Carrier Family 22 (Organic Anion Transporter), Member 6
Term UI T437928
Date03/05/2001
LexicalTag NON
ThesaurusID NLM (2002); PAH Transporter
Term UI T437929
Date03/05/2001
LexicalTag ACX
ThesaurusID NLM (2002); SLC22A6 Transporter
Term UI T432213
Date01/03/2001
LexicalTag ACX
ThesaurusID NLM (2002)

Organic Anion Transport Protein 1 MeSH Descriptor Data 2025