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Cholesterol 24-Hydroxylase MeSH Descriptor Data 2022


MeSH Heading
Cholesterol 24-Hydroxylase
Tree Number(s)
D08.244.453.875.500
D08.244.453.915.025
D08.811.682.690.708.170.497.500
D08.811.682.690.708.170.915.025
D12.776.422.220.453.875.500
D12.776.422.220.453.915.025
Unique ID
D000072556
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072556
Scope Note
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
Entry Term(s)
5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Brain-Specific 24S-Hydroxylase
CYP46A1
Cholestane Tetrol 24-Hydroxylase
Cytochrome P450 46A1
Registry Number
EC 1.14.14.25
Public MeSH Note
2017; CHOLESTEROL 24-HYDROXYLASE was indexed under STEROID HYDROXYLASES 1999-2016
History Note
2017 (1999)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/06/01
Cholesterol 24-Hydroxylase Preferred
Cholestane Tetrol 24-Hydroxylase Narrower
Cytochrome P450 46A1 Narrower
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